Myocarditis is inflammation of the heart muscle (myocardium) which may cause acute heart failure in some patients, while in others, can persist chronically and progress to Dilated Cardiomyopathy (DCM).
Standard treatment for acute myocarditis is supportive heart failure therapy.
Myocarditis may also disguise itself as ischemic, valvular, or hypertensive heart disease.
Enteroviruses cause more than 50% of all U.S. viral myocarditis cases each year but the majority of cases are diagnosed after death (upon autopsy).
Enteroviral infection of the heart has been noted in a significant proportion of cases of Myocarditis and Dilated Cardiomyopathy.
The presence of EV RNA at different stages of disease after acute infection, suggests continued replication of the virus is involved in the progression of the disease.
Coxsackie virus B-3 is the most common EV strain that infects the heart muscle.
CVB induced myocarditis is an important cause of death in adults 20-39 years of age. Myocarditis causes degeneration of the heart muscle, which can be fatal, and often goes undetected.
In the United States, 1 in 4 women die from heart disease, and symptoms can be difficult to recognize. For a review, note signs and symptoms of a heart attack in women: